Swiss researchers wrote recently that higher doses of vitamin D daily may reduce bone fracture risk for the elderly. Their analysis of research studies, published in the Archives of Internal Medicine, found doses higher than 400 I.U. per day reduced non-vertebral fractures by 20 percent and hip fractures by 18 percent.
Dr. Heike A. Bischoff-Ferrari of the University of Zurich Hospital in Switzerland and colleagues examined research involving non-spinal fractures in over 42,000 participants -- including eight trials of 40,886 participants specifically studying hip fractures. When the researchers studied the results of the trials, vitamin D supplements doses of 400 international units per day or lower did not reduce non-spinal or hip fracture risks.
The greater reduction in risk was seen among trial participants whose blood levels of 25-hydroxyvitamin D -- a measure of blood vitamin D levels -- achieved a greater increase.
"Higher doses of vitamin D should be explored in future research to optimize anti-fracture efficacy," the study authors said in a statement. "Our results do not support use of low-dose vitamin D with or without calcium in the prevention of fractures among older individuals."
Other news regarding Vitamin D . . .
Researchers at the California-based non-profit Autoimmunity Research Foundation say that vitamin D may provide short-term relief by lowering inflammation, but it may exacerbate disease symptoms over the long-term in certain auto-immune diseases.
Under such circumstances, supplementation with extra vitamin D may not only be counterproductive but harmful also. They urge people with autoimmune disease to talk to their doctor before taking large doses of supplemental Vitamin D.
A research article on this study has been published in Autoimmunity Reviews.